Host transcription factors in the immediate pro-inflammatory response to the parasitic mite Psoroptes ovis.
BACKGROUND: Sheep scab, caused by infestation with the ectoparasitic mite Psoroptes ovis, results in the rapid development of cutaneous inflammation and leads to the crusted skin lesions characteristic of the disease.We described previously the global host transcriptional response to infestation with P.ovis, elucidating elements of the inflammatory